Drug Dosage Amount
Acyclovir (5%) An Anti-Viral to aid in healing of conditions such as Shingles.
Amantadine (8%) – NMDA receptor antagonist, advantageous because it is not controlled and can be prescribed by providers and physicians without a DEA license. It is also useful for E-scribing.
Baclofen (2%) – An antispasmodic agent used topically for its pain relieving properties. It is a GABA-B receptor agonist which reduces pain, especially in combination with NSAIDs.
Bupivacaine (1%) Local anesthetic with double the duration of action of lidocaine. Sodium channel blocker that works to prevent ectopic neuropathic impulses. Also has anti-inflammatory properties.
Carbamazepine (3%) Anticonvulsant particularly useful for neuralgias. Has sodium channel blocking properties as well.
Clobetasol (0.05%) A mild steroid, helpful in reducing mild, localized inflammatory processes.
Clonidine (0.2%) An Alpha receptor agonist useful in reducing neuropathic pain, especially syndromes with a sympathetic component.
Colchicine (0.5%) Used in the treatment and prevention of Gout flares.
Cyclobenzaprine (2%) Muscle-relaxant. Possesses anti-neuropathic properties as it is structurally related to the tricyclic antidepressants by inhibiting sodium channels.
Deoxy-D-Glucose (2%) A natural anti-viral from Alaskan Red Algae.
Dexamethasone (0.1%) A strong steroid helpful in reducing moderate to severe localized inflammation.
Diclofenac (1-3%) A potent Nonsteriodal Anti-Inflammatory Drug (NSAID) with augmented absorption and depot effect.
Diltiazem (2%) A calcium channel blocker augmenting pain relief with sodium channel blockers and NMDA antagonists. Particularly useful for improving blood flow.
DMSO (10%) A solution that increases skin penetration.
Doxepin (3-5%) A tricyclic antidepressant used topically for pain relief. Doxepin is a sodium channel blocker reducing ectopic impulses. Other properties are anti-histaminic and anesthetic.
Flurbiprofen (5-10%) Treats inflammation and pain of certain arthritic conditions and soft tissue injuries.
Gabapentin (6%) Anticonvulsant which works by 3 mechanisms for neuropathic pain. Best combined with NMDA antagonist (ketamine) for maximum synergistic effect.
Imipramine (3%) A tricyclic anti-depressant commonly used for chronic pain.
Indomethacin (10%) An excellent NSAID primarily used for gout.
Ketamine (10%) Anesthetic. Ketamine also inhibits sodium channels and voltage gated calcium channels.
Ketoprofen (15%) A NSAID that works well in muscle tissue. (Can substitute with Flurbiprofen.)
Ketorolac (0.5%) Potent NSAID inhibiting cyclooxygenase 1 and 2. Ketorolac has increased analgesic properties. Should be limited to short-term acute use (5-7 days).
Lidocaine (5%) A local anesthetic for acute pain relief.
Magnesium (5%) A mineral known for its ability to provide muscle relaxation.
Nifedipine (2%) Calcium channel blocker that works at the gated NMDA receptor but also greatly improves tissue perfusion, improving healing and nerve conduction velocity. Also has been shown to inhibit formation of advanced glycosylation end products.
Orphenadrine (5%) A strong muscle relaxant and pain relieving agent that provides both NMDA receptor and sodium-channel blocking properties. It provides additional benefits when combined with neuropathic and muscle relaxing agents.
Pentoxifylline (5%) A xanthine derivative that improves blood flow in peripheral extremities.
Phenytoin (5%) An anti-convulsant used in combo with other analgesics for chronic pain.
Piroxicam (2%) NSAID also excellent for use in muscle pain.
Guaifenesen (20%) Can help prolong analgesic effects and increase effectiveness of muscle relaxants.
Topiramate (1%) An anticonvulsant with numerous properties contributing to pain relief. Augments the performance of multiple medications by modulating sodium & calcium channels, increasing GABA inhibition, and blocking glutamate neurotransmissions (NMDA receptor).
Verapamil (8%) Calcium channel blocker. In addition to neuropathic use, it has great antifibrogenic properties for use with fibrosis, scarring, strictures and adhesions.